tidyestimate

tidyestimate is a refresh of the excellent ESTIMATE package a package used to determine tumor purity by measuring the amount of infiltrating immune and stromal cells via single-sample gene set enrichment analysis.

While the underlying algorithm remains the same, the ergonomics have been greatly enhanced:

• Instead of having to shuffle around .GCT files, tidyestimate ingests and produces data.frames.
• Since it produces data.frames, rather than intermediate files, it can be piped.
• It does conservative alias matching for gene symbols to allow for compatibility with a wider array of data sets.